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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SF3A1 All Species: 23.94
Human Site: S568 Identified Species: 47.88
UniProt: Q15459 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15459 NP_001005409.1 793 88886 S568 S S A T N I P S S A P P I T S
Chimpanzee Pan troglodytes XP_515067 793 88845 S568 S S A T N I P S S A P P I T S
Rhesus Macaque Macaca mulatta XP_001109090 793 88798 S568 S S A T N I P S S A P P I T S
Dog Lupus familis XP_534733 793 88764 S568 S S A T N I P S S A P P I T S
Cat Felis silvestris
Mouse Mus musculus Q8K4Z5 791 88526 S566 S S A T N I P S S A P P I T S
Rat Rattus norvegicus NP_001100705 791 88569 S566 S S A T N I P S S A P P I T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026643 791 88489 P564 S S A S N P P P S A Q P I T S
Frog Xenopus laevis NP_001085709 802 90334 P562 S A H T I S T P V P P V N S A
Zebra Danio Brachydanio rerio NP_956388 780 87898 P553 P S I P P S M P K P A P P M N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650583 784 88057 S577 P S T K S Q H S H S S Q S Q H
Honey Bee Apis mellifera XP_393373 766 86238 A560 A A A S K P Q A T L K A P P K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RXF1 785 87576 P587 A P R P L G V P M M Q P M H Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.6 98.6 N.A. 98.1 98.1 N.A. N.A. 92.4 86.2 84.1 N.A. 52.4 58.1 N.A. N.A.
Protein Similarity: 100 99.7 99.7 99.2 N.A. 98.3 98.4 N.A. N.A. 95.4 92.3 91 N.A. 68 72.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 20 13.3 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 80 40 20 N.A. 26.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 37 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 67 0 0 0 0 9 0 59 9 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 9 0 9 0 0 0 0 9 9 % H
% Ile: 0 0 9 0 9 50 0 0 0 0 0 0 59 0 0 % I
% Lys: 0 0 0 9 9 0 0 0 9 0 9 0 0 0 9 % K
% Leu: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 9 9 0 0 9 9 0 % M
% Asn: 0 0 0 0 59 0 0 0 0 0 0 0 9 0 9 % N
% Pro: 17 9 0 17 9 17 59 34 0 17 59 75 17 9 0 % P
% Gln: 0 0 0 0 0 9 9 0 0 0 17 9 0 9 9 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 67 75 0 17 9 17 0 59 59 9 9 0 9 9 59 % S
% Thr: 0 0 9 59 0 0 9 0 9 0 0 0 0 59 0 % T
% Val: 0 0 0 0 0 0 9 0 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _